Laboratory of Muscle Biophysics - Molecular Medicine Section

Address: Molecular Medicine Section, NHLI, Faculty of Medicine, Imperial College London,Sir Alexander Fleming Building, South Kensington Campus, London SW7 2AZ Location: Room 225, 2nd floor of Sir Alexander Fleming Building, , Molecular Medicine Section Michael Ferenczi's office: Room 369 on 3rd floor; phone: +44 (0)20 7594 3139 Laboratory phone: +44 (0)20 7594 3040, or extension 43040 if calling from within the campus Section Administrator: Katia Neery. +44 (0)20 7594 3175 Email: m.ferenczi**imperial.ac.uk. MAF's CV MAF's publications list MAF's home page

Current members of the laboratory

12 December 2008:  After skating at the Natural History Museum  WeiHua Song  Tim West  Dmitry Ushakov  Delisa Ibanez-Garcia  Mike Ferenczi  Dale Bickham  Catherine Mansfield  Marco Caremani  So-Jin Holohan

December 2005:  Hugo Parker  Verl Siththanandan  Tim West  Delisa Ibanez-Garcia  Dmitriy Ushakov  Alison Stubbings

May 2005: Top row: Leo Donnelly Tim West Verl Siththanandan Mike Ferenczi Dmitriy Ushakov Bottom row: Delisa Ibanez-Garcia Alison Stubbings

A group picture taken in May 2002 from the top of the Queen's Tower which includes, in the back row, Sergey Bershitsky, Andrey Tsaturyan and Natalia Koubassova, collaborators in the x-ray diffraction projects. On the right is a picture of the inside of our building

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Links relevant to Mike's current interests

Click on icon for details of Seminars, London Muscle Series events and other muscle-related seminars and conferences

Click on link for other links

Click here for the European Biophysical Societies' Association

Click here for the European Biophysics Journal

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Projects

As a way of introduction, here is a representation of 2 sarcomeres from skeletal muscle, shortening according to the sliding filament hypothesis

Time resolved small angle x-ray diffraction of single muscle fibres
Measurement of P_i release in contracting muscle fibres
Measurement of ADP release in permeabilised muscle fibre: strain dependence of ADP release
Development of Total Iinternal Reflection Fluorescence (TIRF) microscopy
Application of TIRF microscopy to visualisation of structural changes in molecular motors
Application of TIRF microscopy to nanoscale physiology
Investigation of strain sensing by muscle molecular engines using Fluorescence Life-Time Imaging Microscopy (FLIM)

Past members of the laboratory

Gabor Hild (until October 2003)	Leo Donnelly (until September 2005) July 2002	Verl Siththanandan (until December 2005) July 2002